Mass Spectrometry and Chromatography

CHROMATOGRAPHY IN BIOINFORMATICS

 The analyzed samples are subjected for sequencing studies either manually or using various software’s. This is studied as Data mining and sequence analysis. HPLC is also used for characterization of different metabolites.

Fingerprinting is a quality model that builds upon spectroscopic and chromatographic technology. It is different from the traditional quality control model in the sense that fingerprinting looks at the “complete information” or comprehensiveness and displays integrated quality information. Comprehensiveness and fuzziness are the two important traits of a fingerprint. The similarity of fingerprints is established through these traits. Fingerprint analysis focuses on accurate identification, and not on precise calculation. The comparison of fingerprints declares similarity and the fingerprints compared do not need to be the same. When it is impossible to find out all the complex components of a medicine fingerprints can be used to check the authenticity of the intrinsic quality of the medicine.